Abstract: Background: The purpose of this study was to evaluate the difference between oral aphthae in Behcet’s Disease (BD) and recurrent aphthous stomatitis (RAS). Methods: In a prospective study 56 cases of BD and 133 RAS were evaluated consecutively. Sex, age of onset, frequency of aphthous lesions, their duration and their mean number at each attack, pathergy test, HLA-B5, HLA-B51 and HLA-B27 were evaluated in both groups. Comparison was made by Student ...
Abstract: Introduction: Pyoderma gangrenosum (PG) like lesion is a Behcet’s disease (BD) skin lesion, which is seen very exceptionally. We report here 2 cases with unusual severe and extensive skin lesions, having an intensive hypersensitivity to needle injection, inducing new lesions. Cases report: The first case is a 42 years old man with a history of 5 years recurrent bipolar aphthosis, skin pustulosis, ocular lesions, and articular involvement. After ...
Abstract: Muco-cutaneous lesions are the most important signs in the diagnostic criteria of Behcet’s Disease (BD), but they are not specific and can be seen in other disease too. Mucous Membrane Lesions: 1- Recurrent oral aphthosis is the most frequent lesion of BD (96.1%0.6). It was divided in major, minor, and herpetiforme aphtosis. There are also Punctiform, Miliaria, and giant aphthosis. The shape and the size of aphthae can vary ...
Abstract: Background: In the literature, some of the skin pustular lesions of BD resembling the pustular lesion of acne vulgaris (AV) was called acneiform lesion of BD. It was suggested that AV was seen more often in BD than in normal population. AV is a common and very frequent skin lesion. The lesions are polymorphic, and are noninflamed (closed or open comedones) or inflamed (papules, pustules, nodules). Objectives: To find if ...
Abstract: Introduction: The diagnosis of Behcet's Disease (BD) is based on clinical criteria. Muco-cutaneous symptoms are the most important among them. Materials and Methods: From 1992 to 1999 we screened systematically all patients attending the Behcet's Disease Research Unit for muco cutaneous lesions. Only recurrent lesions were taken in consideration. Results: Mucous-membrane lesions: 1- Oral aphthosis was seen in 96.1%+ 0.6 of patients. The separation in major and minor aphthosis has no interest. ...
Abstract: There is not yet an effective treatment for all lesions of Behcet's disease and for all patients with Behcet's disease. The highest morbidity is from the ocular lesions. The mortality, although rare, is due to neurological and pulmonary involvement. Thrombosis of the large veins and arteries, also rare, may lead to morbidity and mortality. In daily practice, the best treatment for muco cutaneous lesions is colchicine. Thalidomide may be efficient ...